Vitrocell Systems GmbH als Arbeitgeber

The VITROCELL® Skin Autosampler offers the possibility to take precise samples from the receptor fluid in programmable time intervalls. This makes the autosampler a powerful device for toxicokinetic studies. Once the VITROCELL® Skin module is prepared with skin samples, the robot runs fully automated and delivers the samples in cooled vials. A great tool for lab automation.

http://www.vitrocell.com/skin-exposure/vitrocell-skin-autosampler

For virus research, testing of inhaled drugs, chemicals and nanoparticles at the Air/Liquid Interface (ALI).

The VITROCELL® Cloud α series is our newest innovation and presents a great leap forward in automated exposure of cell cultures. It combines reliable exposure of cell cultures from the respiratory tract with ease of use. This series is our new take on the well-known and frequently published VITROCELL® Cloud systems (6-, 12- and 24-well). Its functionality enables fully automated processes with an all-in-one control unit. Everyday experiments at the Air/Liquid Interface have never been easier.

Our Cloud systems are suitable for nebulization of solutions and suspensions. Possible fields of application are screening of inhaled drugs, virus research and toxicity testing of inhaled substances such as chemicals or nanoparticles.

This video showcases the experiment flow.

VITROCELL® exposure systems are designed for the direct exposure of mammalian cells or tissue at the air/liquid interface - suitable for exposure of all cell types that can be cultivated on microporous membranes. This approach is by far closer to the actual human situation than submerged exposure.

http://www.vitrocell.com/inhalation-toxicology/method/air-liquid-interface

The interaction between the aerosol source, dynamic dilution system, exposure module and auxiliary equipment can be seen in this video.

High precision mass determination in ng resolution. The sensors can be placed in all medium compartments to validate the mass deposition in the module. After the validation they are removed so that the experiment can be carried out using the cell culture inserts. Alternatively, one microbalance sensor can remain in the module to monitor the dose during exposure. The remaining compartments of the module are used for cell culture inserts. VITROCELL® Microbalance Sensor. For dose-response measurement.

http://www.vitrocell.com/inhalation-toxicology/dose-monitoring/microbalance-sensors-software